Cardiogenic Shock Due to Atrial Arrhythmia as the Initial Presentation of Transthyretin Cardiac Amyloidosis

Svenja M Schneider; Kirpal Kochar; Max Ruge; Stefanie Marek-Iannucci; Tanuka Datta; Alexander Hajduczok; Waqas Ullah; Indranee Rajapreyar; Yevgeniy Brailovsky

doi:10.1016/j.jaccas.2022.07.041

Cardiogenic Shock Due to Atrial Arrhythmia as the Initial Presentation of Transthyretin Cardiac Amyloidosis

JACC Case Rep. 2022 Nov 16;4(22):1490-1495. doi: 10.1016/j.jaccas.2022.07.041.

Authors

Svenja M Schneider¹, Kirpal Kochar¹, Max Ruge¹, Stefanie Marek-Iannucci², Tanuka Datta², Alexander Hajduczok², Waqas Ullah², Indranee Rajapreyar², Yevgeniy Brailovsky²

Affiliations

¹ Department of Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
² Division of Cardiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

Abstract

Atrial arrhythmias are common in transthyretin cardiac amyloidosis (ATTR-CA), with a prevalence of ≤80%. They are often not well tolerated. We describe 3 patients with decompensated heart failure and cardiogenic shock precipitated by atrial arrhythmias who ultimately received diagnoses of ATTR-CA. (Level of Difficulty: Intermediate.).

Keywords: ATTR-CA, transthyretin cardiac amyloidosis; CO, cardiac output; ECG, electrocardiogram; EF, ejection fraction; LV, left ventricle; LVEDD, left ventricular end-diastolic diameter; PYP, pyrophosphate; TTE, transthoracic echocardiogram; atrial arrythmias; cardiac amyloid; restrictive physiology; transthyretin cardiac amyloidosis.

Publication types

Case Reports