Interstitial lung disease combined with lung cancer (ILD-LC) has attracted more and more attention. Interstitial lung disease (ILD) is an independent risk factor of lung cancer. ILD and lung cancer have common pathogenesis of promoting fibrosis and promoting cancer, so they are not only comorbidities. This review updated the epidemiology, pathogenesis and incidence and risk factors of treatment-induced acute exacerbation(including surgery, chemotherapy, and radiotherapy)in ILD-LC. The purpose is to improve the understanding, individual management and quality of life of patients in ILD-LC.
间质性肺疾病（ILD）合并肺癌越来越受到关注，ILD是肺癌发生的独立危险因素，两者有共同的促纤维化和促癌的病理生理机制，因此不只是共病。本文对间质性肺疾病合并肺癌的流行病学、发病机制、治疗（包括手术、化疗、放疗）后的获益、急性加重的发生率和危险因素等进行了综述。旨在提高临床医师对间质性肺疾病合并肺癌的认识及诊疗水平，加强个体化管理，改善患者生存质量。.