Intravascular Endothelial Hyperplasia of the Foot

J Foot Ankle Surg. 2023 May-Jun;62(3):458-464. doi: 10.1053/j.jfas.2022.11.007. Epub 2022 Nov 20.

Abstract

Intravascular endothelial hyperplasia is a benign soft tissue mass rarely reported in the foot. Advanced imaging and confirming a benign diagnosis are critical for any soft tissue mass. This paper identifies 2 patients that developed intravascular endothelial hyperplasia tumors which required surgical excision. A 17-year-old male patient presented to clinic complaining of a painful bump to the arch of his right foot which he related to an injury 9 months prior. Magnetic resonance imaging of the right foot revealed a mass within the plantar subcutaneous fat that was serpiginous in nature similar to adjacent branching vessels favoring a low-flow vascular malformation. A 38-year-old female with Multiple Sclerosis presented with complaints of persistent symptoms of pain to the 1st interspace, difficult ambulation and neuritis. Ultrasound and MRI observed solid, multilobulated mass, with internal vascular malformation, MRI describing intrinsic involvement along the abductor musculature and flexor tendons. Both lesions were surgically excised and sent for pathology. Pathology report indicated a diagnosis of intravascular papillary endothelial hyperplasia or Masson's tumor in both cases. Pathology diagnosis of intravascular papillary endothelial hyperplasia is generally good with wide resection leading to low recurrence rates. Both patients in the current study have progressed postoperatively with resolution of symptoms and without recurrence.

Keywords: benign soft tissue masses; intravascular endothelial hyperplasia; tumors.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Diagnosis, Differential
  • Female
  • Foot / diagnostic imaging
  • Foot / pathology
  • Foot / surgery
  • Hemangioendothelioma* / diagnostic imaging
  • Hemangioendothelioma* / surgery
  • Humans
  • Hyperplasia / pathology
  • Hyperplasia / surgery
  • Male
  • Vascular Malformations* / diagnosis
  • Vascular Malformations* / pathology
  • Vascular Neoplasms* / pathology