γδIL17 under control

Guillem Sanchez Sanchez; David Vermijlen

doi:10.1084/jem.20221921

γδIL17 under control

J Exp Med. 2023 Feb 6;220(2):e20221921. doi: 10.1084/jem.20221921. Epub 2022 Dec 15.

Authors

Guillem Sanchez Sanchez^{1

2

3

4}, David Vermijlen^{1

2

3

4}

Affiliations

¹ Department of Pharmacotherapy and Pharmaceutics, Université Libre de Bruxelles (ULB), Brussels, Belgium.
² Institute for Medical Immunology, Université Libre de Bruxelles (ULB), Gosselies, Belgium.
³ ULB Center for Research in Immunology (U-CRI), Université Libre de Bruxelles (ULB), Belgium.
⁴ Walloon Excellence in Lifesciences and Biotechnology (WELBIO) Department, Walloon Excellence Research Institute, Wavre, Belgium.

Abstract

In the mouse, γδ IL17 cells are poised to make IL-17, and these cells have been involved in various infection and cancer models. Edwards et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20211431) now report how different γδIL17 subsets are controlled during homeostasis and cancer.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Homeostasis*
Interleukin-17*
Mice
Neoplasms*

Substances

Interleukin-17