Current developments in antibiotic discovery: Global microbial diversity as a source for evolutionary optimized anti-bacterials: Global microbial diversity as a source for evolutionary optimized anti-bacterials

EMBO Rep. 2023 Jan 9;24(1):e56184. doi: 10.15252/embr.202256184. Epub 2022 Dec 21.

Julian D Hegemann^{1

2}, Joy Birkelbach^{1

2}, Sebastian Walesch^{1

2}, Rolf Müller^{1

2

3}

¹ Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany.
² Department of Pharmacy, Saarland University, Saarbrücken, Germany.
³ Helmholtz International Lab for Anti-Infectives, Saarbrücken, Germany.

Abstract

In light of the pending antibiotic resistance crisis, we need to go back to nature and search for novel anti-bacterial compounds.