Toward a more generalizable blood RNA signature for bacterial and viral infections

Rishi K Gupta; Mahdad Noursadeghi

doi:10.1016/j.xcrm.2022.100866

Toward a more generalizable blood RNA signature for bacterial and viral infections

Cell Rep Med. 2022 Dec 20;3(12):100866. doi: 10.1016/j.xcrm.2022.100866.

Authors

Rishi K Gupta¹, Mahdad Noursadeghi²

Affiliations

¹ Institute of Health Informatics, University College London, London, UK.
² Division of Infection and Immunity, University College London, London, UK. Electronic address: [email protected].

Abstract

Host-response profiles can discriminate different infections. A new 8-gene blood RNA signature to discriminate bacterial and viral infections extends our focus hitherto on the case mix from the US and Europe to include that of low- and middle-income countries.¹ Challenges remain.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Bacterial Infections* / diagnosis
Diagnosis, Differential
Humans
RNA / genetics
Virus Diseases* / diagnosis
Virus Diseases* / genetics

Substances

RNA

Abstract

Publication types

MeSH terms

Substances

Grants and funding