Intravenous thrombolysis for acute ischemic stroke associated with known left ventricular thrombus: safe or not?

Sofia Kitmeridou; Dimitrios Tsiptsios; Dimos Tsalkidis; Evlampia A Psatha; Ioannis Iliopoulos; Nikolaos Aggelousis; Konstantinos Vadikolias

doi:10.1186/s42466-022-00227-3

Intravenous thrombolysis for acute ischemic stroke associated with known left ventricular thrombus: safe or not?

Neurol Res Pract. 2022 Dec 22;4(1):61. doi: 10.1186/s42466-022-00227-3.

Authors

Sofia Kitmeridou¹, Dimitrios Tsiptsios², Dimos Tsalkidis¹, Evlampia A Psatha¹, Ioannis Iliopoulos¹, Nikolaos Aggelousis³, Konstantinos Vadikolias¹

Affiliations

¹ Neurology Department, Democritus University of Thrace, Alexandroupolis, Greece.
² Neurology Department, Democritus University of Thrace, Alexandroupolis, Greece. [email protected].
³ Department of Physical Education and Sport Science, Democritus University of Thrace, Komotini, Greece.

Abstract

Safety and efficacy data on intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) in case of known left ventricular thrombus (LVT) are lacking. We present the case of a 35-year-old male with disabling AIS and known LVT that was treated successfully with intravenous alteplase. Apart from neurological improvement, post-procedural full thrombus lysis was also evident. Even though performing IVT in similar instances constitutes a difficult decision for physicians, it may be reasonable in the context of acute disabling stroke.

Keywords: Intravenous thrombolysis; Left ventricular thrombus; Stroke.

Publication types

Letter