Clonal dynamics using droplet digital polymerase chain reaction in peripheral blood predicts treatment responses in myelodysplastic syndrome

Johanna Illman; Soili Kytölä; Mikko Myllymäki; Freja Ebeling

doi:10.3324/haematol.2022.281595

Clonal dynamics using droplet digital polymerase chain reaction in peripheral blood predicts treatment responses in myelodysplastic syndrome

Haematologica. 2023 Jul 1;108(7):1951-1956. doi: 10.3324/haematol.2022.281595.

Authors

Johanna Illman¹, Soili Kytölä², Mikko Myllymäki³, Freja Ebeling⁴

Affiliations

¹ Department of Internal Medicine, Porvoo Hospital, Helsinki and Uusimaa Hospital District, Porvoo, Finland.
² Laboratory of Genetics, HUS Diagnostic Center, Helsinki University Hospital and Helsinki University, Helsinki, Finland.
³ Helsinki University Hospital, Comprehensive Cancer Center, Division of Hematology, Helsinki, Finland; Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland; Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland.
⁴ Helsinki University Hospital, Comprehensive Cancer Center, Division of Hematology, Helsinki, Finland.

No abstract available

Publication types

Letter

MeSH terms

Clone Cells
Humans
Mutation
Myelodysplastic Syndromes* / diagnosis
Myelodysplastic Syndromes* / drug therapy
Myelodysplastic Syndromes* / genetics
Polymerase Chain Reaction

Grants and funding

Funding: This study was supported by grants from the Helsinki University Hospital Comprehensive Cancer Center, the Southern Finland Regional Cancer Center (FICAN South) and from the Finnish Hematology Association. MM was supported by the Sigrid Juselius Foundation, Academy of Finland, and Finnish Medical Foundation.