Medical therapies, comorbid conditions, and functional performance in people with peripheral artery disease enrolled in clinical trials between 2004 and 2021

Vasc Med. 2023 Apr;28(2):144-146. doi: 10.1177/1358863X221145533. Epub 2023 Jan 1.

Abstract

This study describes changes over time in baseline comorbidities, leg symptoms, functional impairment, and medications of people with lower extremity peripheral artery disease (PAD) randomized into clinical trials designed to improve walking performance.

Trial registration: ClinicalTrials.gov NCT04377126 NCT03743636 NCT03363165 NCT03054519 NCT03871075.

Keywords: exercise; functional assessment; intermittent claudication; opioids; peripheral artery disease (PAD); randomized controlled trial (RCT); statins.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Exercise Therapy
  • Humans
  • Intermittent Claudication
  • Peripheral Arterial Disease* / drug therapy
  • Peripheral Arterial Disease* / therapy
  • Physical Functional Performance
  • Walking

Associated data

  • ClinicalTrials.gov/NCT04377126
  • ClinicalTrials.gov/NCT03743636
  • ClinicalTrials.gov/NCT03363165
  • ClinicalTrials.gov/NCT03054519
  • ClinicalTrials.gov/NCT03871075