COVID-associated non-vasculitic thrombotic retiform purpura of the face and extremities: A case report

Clin Case Rep. 2022 Dec 27;10(12):e6790. doi: 10.1002/ccr3.6790. eCollection 2022 Dec.

Abstract

SARS-CoV-2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID-19 illness. Aggressive anti-COVID-19 therapy with a high-dose steroid regimen led to rapid recovery. This immunothrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.

Keywords: COVID‐19; SARS‐CoV‐2; acral lesions; chilblains; exanthema; purpura; vasculitis.

Publication types

  • Case Reports