Hypogammaglobulinaemia and negative anti-HIV antibodies in AIDS

Arch Dis Child. 1987 Aug;62(8):853-4. doi: 10.1136/adc.62.8.853.

Abstract

Repeated bacterial infections are frequent in children with AIDS owing to the B cell abnormalities produced by HIV infection. We report on two infants who presented with hypogammaglobulinaemia and with no HIV antibodies, but with epidemiological, immunological, and clinical features of AIDS.

MeSH terms

  • Acquired Immunodeficiency Syndrome / immunology*
  • Acquired Immunodeficiency Syndrome / transmission
  • Agammaglobulinemia / immunology*
  • Antibodies, Viral / analysis*
  • HIV / immunology*
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases / immunology
  • Infant, Premature, Diseases / transmission
  • Transfusion Reaction

Substances

  • Antibodies, Viral