Identification and characterization of the genome of a papillomavirus from skin lesions of four-toed hedgehogs (Atelerix albiventris)

Yotaro Shimazaki; Shion Yoneya; Shigeru Fujita; Tomomi Nakashima; Kei Nabeshima; Sumire Sudoh; Katsuki Matsubara; Naka Okumura; Hirotaka Kondo; Koji Nishifuji; Ryota Koba; Yukinobu Tohya

doi:10.1007/s11262-022-01965-x

Identification and characterization of the genome of a papillomavirus from skin lesions of four-toed hedgehogs (Atelerix albiventris)

Virus Genes. 2023 Apr;59(2):234-239. doi: 10.1007/s11262-022-01965-x. Epub 2023 Jan 10.

Authors

Yotaro Shimazaki¹, Shion Yoneya², Shigeru Fujita^{2

3}, Tomomi Nakashima⁴, Kei Nabeshima⁵, Sumire Sudoh⁶, Katsuki Matsubara⁶, Naka Okumura⁷, Hirotaka Kondo⁷, Koji Nishifuji⁸, Ryota Koba⁹, Yukinobu Tohya²

Affiliations

¹ Faculty of Agriculture, Animal Medical Center, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
² Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-shi, Kanagawa, 252-0880, Japan.
³ Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
⁴ IDEXX Laboratories, K.K., 5-8-18 Kajinocho, Koganei-shi, Tokyo, 184-8515, Japan.
⁵ Ecological Risk Assessment and Control Section Center for Environmental Biology and Ecosystem, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba-shi, Ibaraki, 305-8506, Japan.
⁶ Banquet Animal Hospital, 1-3-23 Mishuku, Setagaya-ku, Tokyo, 154-0005, Japan.
⁷ Laboratory of Veterinary Pathology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-shi, Kanagawa, 252-0880, Japan.
⁸ Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
⁹ Laboratory of Veterinary Microbiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa-shi, Kanagawa, 252-0880, Japan. [email protected].

PMID: 36626061
DOI: 10.1007/s11262-022-01965-x

Abstract

The present study describes the clinical and pathological characteristics of skin lesions in two four-toed hedgehogs (Atelerix albiventris). We performed inverse PCR to identify the genome of papillomavirus (PV) in the skin lesions and subsequently sequenced the full genome of the virus, which was tentatively named Atelerix albiventris papillomavirus 1 (AalbPV1). The overall sequences of the viral genomes of both four-toed hedgehogs were identical. This study first identified the presence of a novel PV in Japanese four-toed hedgehogs and provided genetic information about this virus.

Keywords: Four-toed hedgehog; Genetic characterization; Japan; Papillomavirus.

MeSH terms

Animals
Hedgehogs*
Papillomaviridae* / genetics