Sickle cell crisis following intraarticular steroid therapy for rheumatoid arthritis

D D Gladman; C Bombardier

doi:10.1002/art.1780300916

Sickle cell crisis following intraarticular steroid therapy for rheumatoid arthritis

Arthritis Rheum. 1987 Sep;30(9):1065-8. doi: 10.1002/art.1780300916.

Authors

D D Gladman¹, C Bombardier

Affiliation

¹ Rheumatic Disease Unit, University of Toronto, Wellesley Hospital, Ontario, Canada.

PMID: 3663256
DOI: 10.1002/art.1780300916

Abstract

We describe 2 patients who had coexistent rheumatoid arthritis and sickle cell disease. Both patients developed sickle cell crises following intraarticular injection of corticosteroids to control their arthritis. The mechanism of this phenomenon is not clear, but it is suggested that intraarticular steroids be used with caution in patients with sickle cell disease.

Publication types

Case Reports

MeSH terms

Acute Disease
Adrenal Cortex Hormones / adverse effects*
Adult
Anemia, Sickle Cell / chemically induced*
Anemia, Sickle Cell / diagnosis
Arthritis, Rheumatoid / complications*
Arthritis, Rheumatoid / diagnosis
Arthritis, Rheumatoid / drug therapy
Female
Humans
Injections, Intra-Articular
Middle Aged
Recurrence

Substances

Adrenal Cortex Hormones