Evidence on the Preventive Effects of the Postbiotic Derived from Cow's Milk Fermentation with Lacticaseibacillus paracasei CBA L74 against Pediatric Gastrointestinal Infections

Franca Oglio; Cristina Bruno; Serena Coppola; Roberta De Michele; Antonio Masino; Laura Carucci

doi:10.3390/microorganisms11010010

Evidence on the Preventive Effects of the Postbiotic Derived from Cow's Milk Fermentation with Lacticaseibacillus paracasei CBA L74 against Pediatric Gastrointestinal Infections

Microorganisms. 2022 Dec 20;11(1):10. doi: 10.3390/microorganisms11010010.

Authors

Franca Oglio^{1

2}, Cristina Bruno^{1

2}, Serena Coppola^{1

2}, Roberta De Michele¹, Antonio Masino^{1

2}, Laura Carucci^{1

2}

Affiliations

¹ Department of Translational Medical Science, University of Naples Federico II, 80131 Naples, Italy.
² ImmunoNutriton Laboratory at CEINGE Advanced Biotechnologies, University of Naples Federico II, 80131 Naples, Italy.

Abstract

Postbiotics are commonly defined as preparations of inanimate probiotics and/or their cellular components and/or their metabolites/end products that confer health benefits on the host. They have been suggested as a promising strategy to limit infectious diseases. Emerging evidence support the efficacy of the postbiotic derived from cow's milk fermentation with the probiotic Lacticaseibacillus paracasei CBAL74 (FM-CBAL74) in preventing pediatric infectious diseases. We aimed at reviewing the evidence available.

Keywords: COVID-19; Rotavirus; SARS-CoV-2; acute gastroenteritis; butyrate; fermented foods; gut barrier; gut microbiome; infants; probiotics.

Grants and funding

PE0000003/National Recovery and Resilience Plan, European Union - NextGenerationEU "ON Foods - Research and innovation network on food and nutrition Sustainability, Safety and Security - Working ON Foods" .