Gender Differences in the Impact of Coronary Artery Disease and Complete Revascularization on Long-Term Outcomes After Transcatheter Aortic Valve Implantation

Am J Cardiol. 2023 Mar 15:191:133-135. doi: 10.1016/j.amjcard.2023.01.006. Epub 2023 Jan 21.

Abstract

In this study, we compare gender-specific clinical outcomes. We show that outcomes among women after transcatheter aortic valve implantation are significantly influenced by co-existing coronary artery disease (CAD) and its complexity, whereas in men, this is less pronounced. Moreover, we identified a subgroup of women with complex CAD who are at particularly high risk for fatal cardiovascular events, even when compared with men with similar CAD.

Keywords: Coronary artery disease; aortic valve stenosis; percutaneous coronary intervention; transcatheter aortic valve implantation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aortic Valve / surgery
  • Aortic Valve Stenosis* / complications
  • Aortic Valve Stenosis* / surgery
  • Coronary Artery Disease* / complications
  • Coronary Artery Disease* / epidemiology
  • Coronary Artery Disease* / surgery
  • Female
  • Humans
  • Male
  • Percutaneous Coronary Intervention*
  • Risk Factors
  • Sex Factors
  • Transcatheter Aortic Valve Replacement*
  • Treatment Outcome