Advances and opportunities in nanoimaging agents for the diagnosis of inflammatory lung diseases

Nanomedicine (Lond). 2022 Oct;17(25):1981-2005. doi: 10.2217/nnm-2021-0427. Epub 2023 Jan 25.

Abstract

The development of rapid, noninvasive diagnostics to detect lung diseases is a great need after the COVID-2019 outbreak. The nanotechnology-based approach has improved imaging and facilitates the early diagnosis of inflammatory lung diseases. The multifunctional properties of nanoprobes enable better spatial-temporal resolution and a high signal-to-noise ratio in imaging. Targeted nanoimaging agents have been used to bind specific tissues in inflammatory lungs for early-stage diagnosis. However, nanobased imaging approaches for inflammatory lung diseases are still in their infancy. This review provides a solution-focused approach to exploring medical imaging technologies and nanoprobes for the detection of inflammatory lung diseases. Prospects for the development of contrast agents for lung disease detection are also discussed.

Keywords: contrast agents; imaging nanoparticles; inflammatory lungs diseases; medical imaging; respiratory diseases.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents*
  • COVID-19 Testing
  • COVID-19* / diagnostic imaging
  • Contrast Media
  • Diagnostic Imaging / methods
  • Humans
  • Nanoparticles*
  • Nanotechnology / methods

Substances

  • Antineoplastic Agents
  • Contrast Media