Fluorescence turn-off sensing strategy based on Al-based MOF for selective detection of tricresyl phosphate

Tricresyl phosphate (TCP), a notable emerging pollutant with a high bioconcentration factor and biotoxicity, is a typical representative of aryl-organophosphorus flame retardants. The electrochemical and chromatographic technologies used in conventional TCP detection have a variety of drawbacks. Hence, it is crucial to suggest an easy, accurate, and selective method for detecting TCP. In this study, we presented a brand-new method based on NH₂-MIL-53(Al) nanoprobe for the direct luminescence assay of TCP. NH₂-MIL-53(Al) possessed an excellent crystal structure and superior optical qualities. Notably, the introduction of TCP caused a considerable dampening of the photoluminescence signal of the nanoprobe. The fluorescence response based on static quenching was verified by fluorescence lifetime decay curves. The thermodynamic analysis further concluded that TCP and nanoprobe spontaneously produced non-fluorescent complexes due to hydrophobic interaction. The quenching efficiency (F₀-F)/F₀ of the nanoprobe and the TCP concentration displayed good linearity in the scope of 0.3-3.0 μM (R² = 0.996), and the LOD was 0.058 μM under the ideal detection conditions. More significantly, the technique was effectively used to identify TCP in lake and tap water (RSD ≤5.79%), which provided a fresh perspective on how to recognize OPFRs in environmental water.