Cyanide Poisoning and Lactate in Smoke Inhalation

R I Med J (2013). 2023 Feb 1;106(1):14-16.

Abstract

House fires can lead to cyanide poisoning and an associated elevated serum lactate level. Because of delays in obtaining serum cyanide levels, clinical symptoms and serum lactate are often used to guide clinical decision making and antidote administration. However, as this case report identifies, lower levels of serum lactate may in fact correlate with higher levels of serum cyanide that could benefit from treatment with an antidote.

Keywords: antidote; cyanide; emergency medicine; house fire; lactate; toxicology.

Publication types

  • Case Reports

MeSH terms

  • Antidotes / therapeutic use
  • Cyanides* / poisoning
  • Humans
  • Lactic Acid* / therapeutic use
  • Smoke Inhalation Injury* / drug therapy

Substances

  • Antidotes
  • Cyanides
  • Lactic Acid