Age and duration of illness as predictors of ventricular brain ratio (VBR) size in chronic schizophrenic patients. A stepwise regression analysis study

Acta Psychiatr Scand. 1987 Sep;76(3):256-60. doi: 10.1111/j.1600-0447.1987.tb02893.x.

Abstract

The CT scans of 18 chronic schizophrenic patients and 17 controls were evaluated for Ventricular Brain Ratio (VBR) size. A trend for the patient group to have larger VBR than controls was present but did not reach statistical significance at the 5% level. Age was found to be an important correlate of VBR within the patient group but not among controls. In a stepwise multiple-regression model age, among other independent variables, can account for 47% of VBR variance in schizophrenic patients. Linear regression analysis did not reveal significant association between VBR and age in control subjects.

MeSH terms

  • Adult
  • Age Factors
  • Brain / anatomy & histology
  • Brain / diagnostic imaging*
  • Cerebral Ventricles / anatomy & histology*
  • Chronic Disease
  • Humans
  • Male
  • Middle Aged
  • Regression Analysis
  • Schizophrenia / diagnosis*
  • Time Factors
  • Tomography, X-Ray Computed