C-kit-negative transmural gastrointestinal stromal tumor in the stomach: A rare case of upper GI bleeding in Ghana

Samuel Mensah; Ishmael Kyei; Collins Kokuro; Collins Afriyie; Michael Nortey; Ernest Agyei

doi:10.1002/ccr3.6906

C-kit-negative transmural gastrointestinal stromal tumor in the stomach: A rare case of upper GI bleeding in Ghana

Clin Case Rep. 2023 Feb 3;11(2):e6906. doi: 10.1002/ccr3.6906. eCollection 2023 Feb.

Authors

Samuel Mensah^{1

2}, Ishmael Kyei^{1

3}, Collins Kokuro^{1

4}, Collins Afriyie³, Michael Nortey⁵, Ernest Agyei⁶

Affiliations

¹ School of Medicine and Dentistry, College of Health Sciences Kwame Nkrumah University of Science and Technology (KNUST) Kumasi Ghana.
² Department of Surgery KNUST Hospital Kumasi Ghana.
³ Department of Surgery Komfo Anokye Teaching Hospital Kumasi Ghana.
⁴ Department of Medicine Komfo Anokye Teaching Hospital Kumasi Ghana.
⁵ Department of Surgery Cape Coast Teaching Hospital Cape Coast Ghana.
⁶ Department of Pathology Komfo Anokye Teaching Hospital Kumasi Ghana.

Abstract

Upper GI bleeding from GIST is rare in Africa. The C-kit-negative variant is uncommon worldwide. We report a case of a 42-year-old woman managed for upper GI bleeding secondary to stomach GIST, negative for CD117 but positive for DOG 1 and CD 34. The 1-year postsurgery review is uneventful.

Keywords: C‐kit negative; bleeding; gastrointestinal stromal tumor; transmural.

Publication types

Case Reports