A Rare Case of Breast Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma With Amyloid Deposition in a Patient With Sjogren's Syndrome

Cureus. 2023 Jan 27;15(1):e34286. doi: 10.7759/cureus.34286. eCollection 2023 Jan.

Abstract

Marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) of the breast with amyloid deposits is a very rare cause of breast malignancy. Patients who carry a diagnosis of Sjogren's syndrome (SS) have a 5-10% lifetime risk of developing non-Hodgkin lymphoma with MALT lymphoma as the most common histologic subtype. Our case highlights the importance of routine screening mammography in the early detection of such unusual malignancies, and further interventions needed to diagnose and appropriately manage breast MALT lymphoma.

Keywords: amyloid; mucosa-associated lymphoid tissue (malt) lymphoma; primary breast cancer; serum protein electrophoresis (spep); sjogrens syndrome.

Publication types

  • Case Reports