Primary immunodeficiency screening in an infant with cytomegalovirus disease reveals HIV infection

Folia Med (Plovdiv). 2023 Feb 28;65(1):166-170. doi: 10.3897/folmed.65.e72203.

Abstract

Cytomegalovirus is widely spread worldwide, and it is not uncommon for it to complicate the congenital human immunodeficiency virus (HIV) disease as an acquired or congenital coinfection. However, the association of the two infections is not common amongst infants with primary immune deficiencies.We describe a case of a 6-month-old infant with acquired cytomegalovirus and HIV infections, diagnosed in the course of the patient's clinical and laboratory workup for a presumed primary immunodeficiency. To date, this is the first reported case of such a combination in a child from Bulgaria.

Keywords: children; complex viral illness; congenital immune disorder; flow cytometric workup.

Publication types

  • Case Reports

MeSH terms

  • Acquired Immunodeficiency Syndrome*
  • Bulgaria
  • Child
  • Cytomegalovirus
  • Cytomegalovirus Infections* / complications
  • Cytomegalovirus Infections* / diagnosis
  • HIV Infections* / complications
  • HIV Infections* / diagnosis
  • Humans
  • Infant