Investigating the burden of cardiovascular comorbidities in inpatient non-melanoma skin cancer outcomes

While cardiovascular comorbidities can affect the outcomes of a variety of conditions, to our knowledge, few studies have evaluated their impact on non-melanoma skin cancers (NMSC). We studied the National Inpatient Sample to evaluate the impact of cardiovascular comorbidities on NMSC hospitalizations. Our findings displayed higher cost of care (Beta 5053; SE 1150; P < 0.001), length of stay (Beta 1.8; SE 0.394; P < 0.001), and mortality (aOR 2.51; CI 1.49-4.21; P < 0.001) in patients with NMSC who had an associated cardiovascular comorbidity. Specifically, patients with cerebrovascular disease (aOR 3.52; CI 1.18-10.5; P = 0.024), heart failure (aOR 4.02; CI 2.29-7.05; P < 0.001), complicated hypertension (OR 2.05; CI 1.16-3.61; P = 0.013), and pulmonary circulation disease (aOR 3.33; CI 1.13-9.78; P = 0.029) demonstrated greater odds of mortality.