Myocardial tissue changes detected by cardiac MRI in a patient with suspected systemic sarcoidosis

BMC Cardiovasc Disord. 2023 Mar 11;23(1):131. doi: 10.1186/s12872-023-03133-x.

Abstract

Background: The role of cardiac magnetic resonance imaging in the early management of chronic cardiac inflammatory conditions is growing. Our case enlightens the benefit of quantitative mapping in the monitoring and treatment guidance in systemic sarcoidosis.

Case presentation: We report about a 29-year-old man with an ongoing dyspnea and bihilar lymphadenopathy, suggesting sarcoidosis. Cardiac magnetic resonance showed high mapping values, but no scarring. In follow-ups, cardiac remodeling was noted; cardioprotective treatment normalized cardiac function and mapping markers. Definitive diagnosis was achieved in extracardiac lymphatic tissue during a relapse.

Conclusion: This case shows the role that mapping markers can play in the detection and treatment at early stage of systemic sarcoidosis.

Keywords: Cardiac remodeling; Myocardial inflammation; Scar; Systemic sarcoidosis; Tissue mapping.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cardiomyopathies* / diagnosis
  • Heart
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Myocardium / pathology
  • Sarcoidosis* / therapy