Pancreatic adenocarcinoma with brain metastases

Ngie Chang Law; Christopher Lomma

doi:10.1136/bcr-2022-253557

Pancreatic adenocarcinoma with brain metastases

BMJ Case Rep. 2023 Mar 20;16(3):e253557. doi: 10.1136/bcr-2022-253557.

Authors

Ngie Chang Law¹, Christopher Lomma²

Affiliations

¹ Medical Oncology Department, Fiona Stanley Hospital, Murdoch, Western Australia, Australia [email protected].
² Medical Oncology Department, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.

PMID: 36941017
PMCID: PMC10030487 (available on 2025-03-20)
DOI: 10.1136/bcr-2022-253557

Abstract

Brain metastases are rare for patients with pancreatic adenocarcinoma. The incidence of brain metastasis may increase as improved systemic treatment regimens improve overall survival. Given the low incidence of brain metastasis, recognition of disease and management remain a challenge. We report three cases of metastatic pancreatic adenocarcinoma with brain metastases, review the literature and discuss its management principles.

Keywords: Neurosurgery; Pancreatic cancer; Radiotherapy.

Publication types

Case Reports

MeSH terms

Adenocarcinoma* / pathology
Brain Neoplasms* / diagnostic imaging
Brain Neoplasms* / secondary
Brain Neoplasms* / therapy
Humans
Incidence
Pancreatic Neoplasms* / pathology