COVID-19-associated AMPA-R and CRMP-5 autoimmune encephalitis in a patient with thymoma and myasthenia gravis

Jenelle Raynowska; Victoria Wu; Max Kazer; Jamie Nicole LaBuzetta; Dominic Ferrey; Anastasie Dunn-Pirio

doi:10.1002/ccr3.7064

COVID-19-associated AMPA-R and CRMP-5 autoimmune encephalitis in a patient with thymoma and myasthenia gravis

Clin Case Rep. 2023 Mar 19;11(3):e7064. doi: 10.1002/ccr3.7064. eCollection 2023 Mar.

Authors

Jenelle Raynowska¹, Victoria Wu¹, Max Kazer¹, Jamie Nicole LaBuzetta¹, Dominic Ferrey¹, Anastasie Dunn-Pirio¹

Affiliation

¹ Department of Neurosciences University of California, San Diego La Jolla California USA.

Abstract

Thymomas are associated with autoimmune disease, most commonly myasthenia gravis, and rarely with autoimmune encephalitis. More recently, viral triggers including COVID-19 have also been implicated in autoimmunity. We present a case of antibody-positive autoimmune encephalitis that developed in the setting of COVID-19 in a patient with thymomatous myasthenia gravis.

Keywords: COVID‐19; autoimmune encephalitis; myasthenia gravis; thymoma.

Publication types

Case Reports