Cholecystoappendiceal Fistula From Appendiceal Adenocarcinoma Requiring a Right Hemicolectomy With Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy

Am Surg. 2023 Aug;89(8):3605-3608. doi: 10.1177/00031348231167402. Epub 2023 Mar 23.

Abstract

Bilioenteric fistulae are rare and difficult to manage complications of chronic cholecystitis. While cholecystoduodenal and cholecystocolic fistulae are more common, a cholecystoappendiceal fistula is an extremely rare finding. We report the presentation and operative management of a 59-year-old male with cholecystoappendiceal fistula and associated abscess in the gallbladder fossa. The patient was appropriately resuscitated, the abscess drained by interventional radiology, and after a complete workup, underwent a laparoscopic appendectomy and cholecystectomy. Pathology revealed moderately differentiated appendiceal adenocarcinoma requiring a right hemicolectomy with cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). He has recovered well postoperatively with no complications. This case highlights the importance of having a very high index of suspicion for underlying malignancy when managing a fistula of any kind. To the best of our understanding, this is only the second reported case of a cholecystoappendiceal fistula.

Keywords: cholecystoappendiceal fistula; cholecystoenteric fistula; chronic cholecystitis; hyperthermic intraperitoneal chemotherapy; laparoscopic appendectomy; laparoscopic cholecystectomy.

Publication types

  • Case Reports

MeSH terms

  • Abscess / surgery
  • Adenocarcinoma* / surgery
  • Adenocarcinoma* / therapy
  • Appendiceal Neoplasms* / complications
  • Appendiceal Neoplasms* / pathology
  • Appendiceal Neoplasms* / therapy
  • Colectomy
  • Cytoreduction Surgical Procedures
  • Fistula* / surgery
  • Humans
  • Hyperthermia, Induced*
  • Hyperthermic Intraperitoneal Chemotherapy
  • Male
  • Middle Aged
  • Peritoneal Neoplasms* / pathology