An amphiphilic macrocyclic acylhydrazone dimer: Facile synthesis and dual channel detection and removal of phthalate anion

Zhengning Shu; Shitao Sun; Ning Gu; Zhichao Yang; Yongxin Shang; Yi Yang; Mingyu Xia; Bin Lin; Peng Yang

doi:10.1016/j.aca.2023.341093

An amphiphilic macrocyclic acylhydrazone dimer: Facile synthesis and dual channel detection and removal of phthalate anion

Anal Chim Acta. 2023 May 1:1253:341093. doi: 10.1016/j.aca.2023.341093. Epub 2023 Mar 16.

Authors

Zhengning Shu¹, Shitao Sun², Ning Gu¹, Zhichao Yang¹, Yongxin Shang¹, Yi Yang¹, Mingyu Xia³, Bin Lin⁴, Peng Yang⁵

Affiliations

¹ Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China.
² Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, China.
³ School of Life Sciences and Biological Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, China. Electronic address: [email protected].
⁴ Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China. Electronic address: [email protected].
⁵ Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, China. Electronic address: [email protected].

PMID: 36965995
DOI: 10.1016/j.aca.2023.341093

Abstract

Despite the large number of dicarboxylates' receptors, the dual channel ones capable of recognizing and removing of phthalate anion are rare and the task remains challenging. In this paper, a facilely synthesized amphiphilic macrocyclic acylhydrazone dimer (AMAD) can not only detect phthalate anion selectively, through both color changes and turn-on fluorescence in solution as well as in solid state, but is also able to remove it from either water or organic solvents. The current study paves the way for the search of more multiple functional receptors of dicarboxylates anions.

Keywords: Chromogenic; Dual channel; Fluorescent; Macrocycle; Recognition; Sensor.