Detrimental effects of sickle cell disease and hydroxycarbamide on ovarian reserve but uncertain impact on fertility

Affiliations

• ¹ Biotherapy Department, French National Sickle Cell Referral Center, Clinical Investigation Center, Hôpital Necker, Assistance-Publique Hôpitaux de Paris, Paris, France.
• ² Laboratory of Excellence on Red Blood Cell Labex GR-Ex, Paris, France.
• ³ University of Paris Cité, Paris, France.
• ⁴ Automated Biological Diagnosis Department, AP-HP.Centre-University of Paris Cité, Cochin Hospital, Paris, France.
• ⁵ Department of Reproductive Biology CECOS, AP-HP.Centre-University of Paris Cité, Cochin Hospital, Paris, France.
• ⁶ Internal Medicine Department, French National Sickle Cell Referral Center, Hôpital Européen Georges Pompidou, Assistance-Publique Hôpitaux de Paris, Paris, France.
• ⁷ INSERM U1163, CNRS 8254, Institut IMAGINE, Hôpital Necker, Assistance-Publique Hôpitaux de Paris, Paris, France.
• ⁸ Department of Gynecology Obstetrics II and Reproductive Medicine, AP-HP.Centre-University of Paris Cité, Cochin Hospital, Paris, France.
• ⁹ Department "Development, Reproduction and Cancer" Institut Cochin, INSERM U1016, Paris, France.