Peridevice Leak After Left Atrial Appendage Occlusion: Incidence, Mechanisms, Clinical Impact, and Management

JACC Cardiovasc Interv. 2023 Mar 27;16(6):627-642. doi: 10.1016/j.jcin.2022.12.006.

Abstract

Left atrial appendage occlusion is an increasingly adopted stroke prevention strategy in patients with atrial fibrillation. However, peridevice leaks after the procedure are not infrequent and have recently been shown to confer a higher risk for subsequent ischemic events. In this paper, the authors review the available research on the frequency, mechanisms, clinical significance, and management of peridevice leak after percutaneous left atrial appendage occlusion.

Keywords: anticoagulation; atrial fibrillation; left atrial appendage occlusion; stroke.

Publication types

  • Review

MeSH terms

  • Atrial Appendage* / diagnostic imaging
  • Atrial Fibrillation* / complications
  • Atrial Fibrillation* / diagnosis
  • Atrial Fibrillation* / epidemiology
  • Cardiac Catheterization / adverse effects
  • Humans
  • Incidence
  • Stroke* / epidemiology
  • Stroke* / etiology
  • Stroke* / prevention & control
  • Treatment Outcome