Lung adeno-squamous carcinoma modeling using oncogenic KRAS activation in human embryonic stem cell-derived alveolar organoids

Genes Dis. 2022 Apr 7;10(1):33-36. doi: 10.1016/j.gendis.2022.03.015. eCollection 2023 Jan.

Jianqi Feng¹, Lian Li¹, Zhihong Tan¹, Shanshan Zhao¹, Xin Zhang¹, Jinhong Wang², Yaping Ye³, Ying Lin^{1

4}, Zhili Rong^{1

5

6

4}

¹ Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou, Guangdong 510515, China.
² Department of Respiration, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong 510630, China.
³ Department of Pathology, Nanfang Hospital and School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong 510515, China.
⁴ Experimental Education/Administration Center, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong 510515, China.
⁵ Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong 510091, China.
⁶ Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou, Guangdong 510005, China.

No abstract available