Intracranial Myroides odoratimimus Infection After EVD Successfully Treated with Intravenous Plus Intraventricular Tigecycline: A Case Report

Ling-Zhi Jiang; Ye Shen; Feng Liang; Xiang-Ming Ye; Jing Chen; Yan-Mei Yu

doi:10.2147/IDR.S403088

Intracranial Myroides odoratimimus Infection After EVD Successfully Treated with Intravenous Plus Intraventricular Tigecycline: A Case Report

Infect Drug Resist. 2023 Apr 1:16:1955-1963. doi: 10.2147/IDR.S403088. eCollection 2023.

Authors

Ling-Zhi Jiang¹, Ye Shen¹, Feng Liang¹, Xiang-Ming Ye¹, Jing Chen¹, Yan-Mei Yu¹

Affiliation

¹ Center for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.

Abstract

Intracranial infections are the most serious and common postoperative complications with significant mortality and morbidity. Myroides odoratimimus (M. odoratimimus), a Gram-negative environmental species and an opportunistic microorganism, predominantly infects immunocompromised individuals. Limited clinical experiences and documented multidrug resistance have resulted in a scarcity of data on the treatment of M. odoratimimus infections. As far as we know, this is the first reported case of an intracranial M. odoratimimus infection with external ventricular drains (EVD) that was effectively treated with a combination of intravenous and intraventricular tigecycline in an immunocompetent adult host.

Keywords: M. odoratimimus; Myroides odoratimimus; immunocompetent host; intracranial infection; tigecycline.

Publication types

Case Reports

Grants and funding

This study was partially supported by the project “lncRNA-UCA1-microRNA-143-Notch1 regulates autophagy in myocardial ischemia reperfusion injury induced by cardiopulmonary bypass.” (No. 2020KY041).