Clinical effect of MRZE chemotherapy combined with cluster nursing intervention in the treatment of patients with pulmonary tuberculosis and its influence on the levels of inflammatory factors and CT signs

Biotechnol Genet Eng Rev. 2024 Nov;40(3):2520-2534. doi: 10.1080/02648725.2023.2200305. Epub 2023 Apr 12.

Abstract

The study aimed to analyze the clinical effect of MRZE chemotherapy combined with cluster nursing intervention and treatment of pulmonary tuberculosis patients and its influence on CT signs. A total of 94 patients treated in our hospital from March 2020 to October 2021 were selected as the research object. Both groups were treated with MRZE chemotherapy regimen. Patients in the control group received routine nursing mode on this basis, and patients in the observation group received cluster nursing on the basis of the control group. The clinical efficacy, adverse reactions, compliance and nursing satisfaction, detection rate of immune function pulmonary oxygen index and pulmonary function CT signs and the level of inflammatory factors before and after nursing were compared between the two groups. The total effective rate of the observation group was significantly higher than that of the control group. The compliance rate and nursing satisfaction of the observation group were significantly higher than those of the control group. The differences of adverse reactions between the observation and control groups were statistically significant. After nursing, the scores of tuberculosis prevention and control of tuberculosis infection route, tuberculosis symptoms, tuberculosis policy and tuberculosis infection awareness in the observation group were significantly higher than those in the control group, and the differences were statistically significant. MRZE chemotherapy combined with cluster nursing intervention model for pulmonary tuberculosis patients can effectively improve the treatment compliance and nursing satisfaction of patients, and it is worthy of clinical promotion and application.

Keywords: CT signs; Cluster nursing intervention; MRZE chemotherapy; pulmonary tuberculosis.

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use
  • Female
  • Humans
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed
  • Tuberculosis, Pulmonary* / drug therapy

Substances

  • Antitubercular Agents