Automatic quantification method of eosinophilic degranulation in tissues: Application for the study of eosinophilic disorders

Frédéric Dezoteux; Antonino Bongiovanni; Meryem Tardivel; Arnaud Dendooven; Jean-Baptiste Gibier; Geoffrey Mortuaire; Solène Audry; Marie-Hélène Gevaert; Nicolas Van Poucke; Emilie Anglo; Guillaume Lefèvre; Delphine Staumont-Sallé

doi:10.1111/cea.14323

Automatic quantification method of eosinophilic degranulation in tissues: Application for the study of eosinophilic disorders

Clin Exp Allergy. 2023 Aug;53(8):862-865. doi: 10.1111/cea.14323. Epub 2023 Apr 18.

Authors

Affiliations

¹ CHU Lille, Univ. Lille, Service de Dermatologie, U1286 Inserm INFINITE - Institute for Translational Research in Inflammation, Lille, France.
² CEREO, National Reference Center for Hypereosinophilic Syndromes, Lille, France.
³ CNRS, Inserm, CHU Lille, Univ. Lille, Institut Pasteur de Lille, US 41-UAR 2014-PLBS, Lille, France.
⁴ CHU Lille, U1286 Inserm INFINITE, Univ. Lille, Institute for Translational Research in Inflammation, Lille, France.
⁵ CHU Lille, Univ. Lille, Institut de Pathologie, Centre de Biopathologie, Lille, France.
⁶ CHU Lille, Service d'Otorhinolaryngologie, Univ. Lille, U1286 Inserm INFINITE - Institute for Translational Research in Inflammation, Lille, France.
⁷ CHU Lille, Univ. Lille, Institut d'Immunologie, Médecine Interne et Immunologie Clinique, U1286 Inserm INFINITE - Institute for Translational Research in Inflammation, Lille, France.

PMID: 37072930
DOI: 10.1111/cea.14323

No abstract available

Keywords: EPX; degranulation surface; eosinophil aggregates; eosinophil degranulation; eosinophil peroxidase; eosinophils; extracellular granules.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Degranulation*
Eosinophils*
Humans