Cerebral venous sinus thrombosis following ChAdOx1 nCoV-19 AstraZeneca COVID-19 vaccine

Shyam S Sharma; Giosue Gulli; Pankaj Sharma

doi:10.1177/20480040231169464

Cerebral venous sinus thrombosis following ChAdOx1 nCoV-19 AstraZeneca COVID-19 vaccine

JRSM Cardiovasc Dis. 2023 Apr 11:12:20480040231169464. doi: 10.1177/20480040231169464. eCollection 2023 Jan-Dec.

Authors

Shyam S Sharma¹, Giosue Gulli², Pankaj Sharma^{3

4}

Affiliations

¹ Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.
² Department of Stroke Medicine, Ashford & St Peter's Hospitals NHS Foundation Trust, Surry, UK.
³ Institute of Cardiovascular Research, Royal Holloway University of London (ICR2UL), London, UK.
⁴ Department of Clinical Neuroscience, Imperial College Healthcare NHS Trust, London, UK.

Abstract

A woman in her mid-twenties was admitted with headache, ultimately leading to a diagnosis of cerebral venous sinus thrombosis 10 days after receiving a first dose of the AstraZeneca ChAdOx1 nCoV-19 vaccine (Vaxzevria). We report this case from clinical investigations to outcomes and discuss the issues raised by it regarding the ChAdOx1 nCoV-19 vaccine.

Keywords: Acute stroke syndromes; COVID-19; cerebral venous thrombosis; vaccination.

Publication types

Case Reports