Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics

Emerg Infect Dis. 2023 May;29(5):1076-1078. doi: 10.3201/eid2905.221456.

Abstract

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

Keywords: Belgium; Costa Rica; Leishmania; Panama; cutaneous parasites; genetics; genomics; interspecific hybridization; leishmaniasis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Genomics
  • Humans
  • Leishmania* / genetics
  • Leishmaniasis, Cutaneous* / parasitology
  • Parasites
  • Triploidy*