Healthy aging and the human gut microbiome: why we cannot just turn back the clock

Tomasz Wilmanski; Sean M Gibbons; Nathan D Price

doi:10.1038/s43587-022-00294-w

Healthy aging and the human gut microbiome: why we cannot just turn back the clock

Nat Aging. 2022 Oct;2(10):869-871. doi: 10.1038/s43587-022-00294-w.

Authors

Tomasz Wilmanski¹, Sean M Gibbons^{2

3

4}, Nathan D Price^{5

6

7}

Affiliations

¹ Institute for Systems Biology, Seattle, WA, USA.
² Institute for Systems Biology, Seattle, WA, USA. [email protected].
³ Department of Bioengineering, University of Washington, Seattle, WA, USA. [email protected].
⁴ eScience Institute, University of Washington, Seattle, WA, USA. [email protected].
⁵ Institute for Systems Biology, Seattle, WA, USA. [email protected].
⁶ Department of Bioengineering, University of Washington, Seattle, WA, USA. [email protected].
⁷ Thorne HealthTech, New York, NY, USA. [email protected].

Abstract

The aging research field has largely focused on reversing aging-related changes in the body. However, emerging evidence about the gut microbiome indicates that it may not be optimal to just turn back the clock. Here, we advocate for a more tailored and function-focused approach promoting health across the lifespan.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Gastrointestinal Microbiome*
Healthy Aging*
Humans
Microbiota*

Grants and funding

R01 DK133468/DK/NIDDK NIH HHS/United States