Cell survival pathways targeted in rare lung disease affecting women

Sci Adv. 2023 May 10;9(19):eadi1215. doi: 10.1126/sciadv.adi1215. Epub 2023 May 10.

Abstract

Novel drug targets are identified in lymphangioleiomyomatosis (LAM), a rare disease in women. These targets focus on uterine transcription factors necessary for LAM cell survival.

Publication types

  • Review

MeSH terms

  • Cell Survival
  • Female
  • Humans
  • Lung / metabolism
  • Lung Neoplasms*
  • Lymphangioleiomyomatosis* / drug therapy
  • Lymphangioleiomyomatosis* / metabolism
  • Rare Diseases