Novel Mutation of Tyrosinemia in a Child With Hypophosphatemic Rickets

JPGN Rep. 2022 Feb 25;3(2):e176. doi: 10.1097/PG9.0000000000000176. eCollection 2022 May.

Abstract

Tyrosinemia is an inherited metabolic disease of fumarylacetoacetate enzyme. A male infant presented to us with clinical features of rickets, floppiness, and a deranged coagulation profile. A novel mutation causing Tyrosinemia was discovered on the basis of genetic sequencing.

Keywords: deranged coagulation; hypotonia; liver transplant; renal tubulopathy.

Publication types

  • Case Reports