Photodynamic therapy in a patient with perianal extramammary Paget's disease

Photodiagnosis Photodyn Ther. 2023 Jun:42:103603. doi: 10.1016/j.pdpdt.2023.103603. Epub 2023 May 9.

Abstract

Extramammary Paget's disease is a rare neoplasm of apocrine gland-bearing areas of the skin. One of the most common localizations of such a tumor is the perianal area. Surgery is the most frequently reported therapy. However, it is an invasive procedure and complicated by a high recurrence rate. An alternative to surgical treatment may be non-invasive photodynamic therapy. We describe in this article the case of a 69-year-old patient with extramammary Paget's disease (a large tumor in the perianal area 22 × 18 cm) successfully treated with chlorin e6 photodynamic therapy.

Keywords: Chlorin e6; Extramammary Paget's disease; Photodynamic therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bone Neoplasms*
  • Breast Neoplasms*
  • Female
  • Humans
  • Paget Disease, Extramammary* / drug therapy
  • Paget Disease, Extramammary* / pathology
  • Photochemotherapy* / methods
  • Photosensitizing Agents / therapeutic use
  • Skin Neoplasms*

Substances

  • Photosensitizing Agents