Vulvovaginal Complaints as the First Manifestation of Crohn's Disease in Children: Case Report

J Pediatr Adolesc Gynecol. 2023 Oct;36(5):494-496. doi: 10.1016/j.jpag.2023.05.007. Epub 2023 May 15.

Abstract

Background: Crohn's disease, a chronic gastrointestinal inflammatory condition, can involve gynecological structures. Rectovaginal or rectovestibular involvement may be the first sign in the pediatric population and may result in delayed diagnosis and treatment.

Case: A 9-year-old premenarchal female with chronic constipation and poor growth presented to the pediatric gynecologist for evaluation of persistent vulvovaginal discharge and vulvar irritation. Examination under anesthesia revealed a rectolabial fistula; colonoscopy was diagnostic of Crohn's disease. Immunotherapy resulted in improvement of symptoms and anatomical changes.

Summary and conclusion: In cases of persistent vulvar complaints in a child without clear diagnosis, a high index of suspicion for a non-gynecologic diagnosis is necessary. Collaboration between pediatric gynecologists, gastroenterologists, and surgeons can result in prompt diagnosis and treatment of genital Crohn's disease.

Keywords: Crohn's disease; Inflammatory disease; Vulvar disease; Vulvar edema.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Crohn Disease* / complications
  • Crohn Disease* / diagnosis
  • Female
  • Fistula*
  • Humans
  • Vulva