Hybrid closed-loop systems can help patients with extreme fear of hypoglycemia or hyperglycemia

Hormones (Athens). 2023 Sep;22(3):453-456. doi: 10.1007/s42000-023-00451-9. Epub 2023 May 17.

Abstract

Fear of hypoglycemia and hyperglycemia can lead to inappropriate diabetes self-management and untoward health outcomes. We report two patients, representative of these opposite conditions, who benefited from hybrid closed-loop technology. In the patient with fear of hypoglycemia, time in range improved from 26 to 56% and the patient did not present with severe hypoglycemia. Meanwhile, the patient with hyperglycemia aversiveness had a drastic reduction in time below range, from 19 to 4%. We conclude that hybrid closed-loop technology was an effective tool for improvement of glucose values in two patients with fear of hypoglycemia and hyperglycemia aversiveness, respectively.

Keywords: Fear of hypoglycemia; Hybrid closed-loop systems; Hyperglycemia aversiveness.

Publication types

  • Review

MeSH terms

  • Blood Glucose
  • Blood Glucose Self-Monitoring
  • Diabetes Mellitus, Type 1* / drug therapy
  • Fear
  • Humans
  • Hyperglycemia* / prevention & control
  • Hypoglycemia* / prevention & control
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Insulin Infusion Systems

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin