Rubella virus-associated necrotizing granulomatous inflammation with extensive eyelid, ocular, and orbital involvement

Pediatr Dermatol. 2023 Nov-Dec;40(6):1107-1111. doi: 10.1111/pde.15337. Epub 2023 May 18.

Abstract

We present a case of cutaneous granulomatous disease associated with rubella virus in a 4-year-old girl without an identifiable immunodeficiency. In this case, a combination of anti-inflammatory, anti-viral, and anti-neutrophil therapies successfully treated vision-threatening eyelid, conjunctival, scleral, and orbital inflammation.

Keywords: granuloma; rubella; vaccine.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Eyelids
  • Female
  • Granuloma / drug therapy
  • Humans
  • Immunologic Deficiency Syndromes*
  • Inflammation / complications
  • Rubella virus
  • Skin Diseases* / complications