Zn-ProPhenol catalyzed asymmetric inverse-electron-demand Diels-Alder reaction

Chem Commun (Camb). 2023 Jun 1;59(45):6929-6932. doi: 10.1039/d3cc01641b.

Abstract

The first Zn-ProPhenol catalyzed asymmetric inverse-electron-demand Diels-Alder reaction has been accomplished. This protocol was carried out by a dual-activation mode under mild conditions, allowing the preparation of various biologically important dihydropyrans in good yields with excellent stereoselectivities.