Challenges in the transfusion management of a 15-month-old pediatric patient with Bombay blood group phenotype

Transfus Apher Sci. 2023 Aug;62(4):103727. doi: 10.1016/j.transci.2023.103727. Epub 2023 May 12.

Abstract

Bombay blood group phenotype is often mistyped as O group which can lead to hemolytic transfusion reactions. There are a very few case reports of Bombay blood group phenotype in pediatric age group. Herein, we report an interesting case of Bombay blood group phenotype in a fifteen-month-old pediatric patient who presented with features of raised intracranial pressure and required an emergency surgery. The Bombay blood group was detected on detailed immunohematology work up which was further confirmed by molecular genotyping. The challenges faced in developing countries for transfusion management of such a case have been discussed.

Keywords: Bombay blood group; Molecular blood grouping; Rare blood group registry.

MeSH terms

  • ABO Blood-Group System / genetics
  • Blood Grouping and Crossmatching
  • Blood Transfusion*
  • Humans
  • Phenotype
  • Transfusion Reaction*

Substances

  • ABO Blood-Group System