A nested variant of urothelial carcinoma of the urethra and urinary bladder: A case report and review of literature

Ali Taghizadeh Kermani; Mahmoud Reza Kalantari; Zohreh Pishevar Feizabad; Soudeh Arastouei

doi:10.1002/ccr3.7360

A nested variant of urothelial carcinoma of the urethra and urinary bladder: A case report and review of literature

Clin Case Rep. 2023 May 25;11(6):e7360. doi: 10.1002/ccr3.7360. eCollection 2023 Jun.

Authors

Ali Taghizadeh Kermani¹, Mahmoud Reza Kalantari², Zohreh Pishevar Feizabad¹, Soudeh Arastouei¹

Affiliations

¹ Cancer Research Center Mashhad University of Medical Sciences Mashhad Iran.
² Department of Pathology, Faculty of medicine Mashhad University of Medical Sciences Mashhad Iran.

Abstract

Nested variant of urothelial carcinoma (NV-UC) is an extremely rare cancer with a nonspecific presentation. It is usually identified at a late stage, which makes the treatment challenging. Herein we report the case of a 52-year-old woman with an advanced NV-UC treated by anterior exenteration after a poor response to neoadjuvant chemotherapy. One year after completion of adjuvant radiotherapy, the patient remains disease-free.

Keywords: bladder neoplasm; chemotherapy; nested variant; urothelial carcinoma.

Publication types

Case Reports