Emergence of Malignant T-Cell Intraclonal CDR3 Variants in Mycosis Fungoides

JAMA Dermatol. 2023 Aug 1;159(8):888-890. doi: 10.1001/jamadermatol.2023.0826.

Authors

Laura Gleason¹, Alexa Cohen¹, Andrew P South¹, Pierluigi Porcu², Neda Nikbakht¹

Affiliations

¹ Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.
² Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

PMID: 37285150
DOI: 10.1001/jamadermatol.2023.0826

No abstract available

Plain language summary

This case report describes 3 patients with mycosis fungoides with CDR3 variants.

MeSH terms

Humans
Mycosis Fungoides* / diagnosis
Mycosis Fungoides* / pathology
Skin Neoplasms* / diagnosis
Skin Neoplasms* / genetics
Skin Neoplasms* / pathology
T-Lymphocytes / pathology