Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A

Protein Cell. 2023 Jun 7;14(6):464-468. doi: 10.1093/procel/pwac033.

Authors

Yuxiang Chen^{1

2

3

4}, Bo Chen¹, Tingting Wu¹, Fangfang Zhou¹, Fei Xu^{1

2

3

4}

Affiliations

¹ iHuman Institute, ShanghaiTech University, Shanghai 210210, China.
² School of Life Science and Technology, ShanghaiTech University, Shanghai 210210, China.
³ Center for Excellence in Molecular Cell Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
⁴ University of Chinese Academy of Sciences, Beijing 100049, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cryoelectron Microscopy
Dynorphins* / metabolism
Humans
Receptors, Opioid, kappa* / agonists
Receptors, Opioid, kappa* / metabolism

Substances

Dynorphins
Receptors, Opioid, kappa