Haematological challenges in cardiogenic shock

Curr Opin Crit Care. 2023 Aug 1;29(4):392-396. doi: 10.1097/MCC.0000000000001064. Epub 2023 Jun 12.

Abstract

Purpose of review: Cardiogenic shock (CS) remains a very challenging condition with high mortality, despite the advances in therapeutic options. Haematological complications, including coagulopathy and haemolysis, frequently arise in these critically ill patients in CS, especially if they need percutaneous mechanical circulatory support (pMCS), and impair the outcome. This stresses the urgent need for further advancement of this field.

Recent findings: Here, we discuss the different haematological challenges during CS and additional pMCS. Furthermore, we propose a management strategy aiming for restabilization of this precarious haemostatic balance.

Summary: In this review, pathophysiology and management of coagulopathies during CS and pMCS are discussed, as well as the need for further studies in this field.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Heart-Assist Devices* / adverse effects
  • Humans
  • Shock, Cardiogenic* / etiology
  • Treatment Outcome