Individualized dosing guidelines for PEGasparaginase and factors influencing the clearance: a population pharmacokinetic model

Affiliations

• ¹ Department of pediatric oncology and hematology, Sophia Children's Hospital - Erasmus MC, Rotterdam.
• ² Department of Hospital Pharmacy, Amsterdam University Medical Center, University of Amsterdam, Amsterdam.
• ³ Princess Máxima Center for Pediatric Oncology, Utrecht.
• ⁴ Department of pediatric oncology and hematology, Sophia Children's Hospital - Erasmus MC, Rotterdam, the Netherlands; Princess Máxima Center for Pediatric Oncology, Utrecht. [email protected].